Antifungal Susceptibilities Among Different Serotypes Of Cryptococcus Gattii And Cryptococcus Neoformans

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Date

2009-01

Authors

Thompson, George R.
Wiederhold, Nathan P.
Fothergill, Annette W.
Vallor, Ana C.
Wickes, Brian L.
Patterson, Thomas F.

Journal Title

Journal ISSN

Volume Title

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Abstract

We measured antifungal activity against 128 cryptococcal isolates (86 of C. neoformans and 42 of C. gattii) to determine if differences in serotype susceptibility exist. Contrary to previous results, we found no serotype susceptibility differences. Isavuconazole, posaconazole, and voriconazole demonstrated excellent potency against each isolate and serotype, including isolates with reduced fluconazole susceptibilities.

Department

Pharmaceutical Sciences

Description

Keywords

in-vitro susceptibilities, 2 varieties, epidemiology, infection, drugs, host, microbiology, pharmacology & pharmacy

LCSH Subject Headings

Citation

Thompson GR, Wiederhold NP, Fothergill AW, Vallor AC, Wickes BL, Patterson TF. Antifungal Susceptibilities among Different Serotypes of Cryptococcus gattii and Cryptococcus neoformans. Antimicrobial Agents and Chemotherapy, 2009;53(1):309-311. doi:10.1128/AAC.01216-08

URI

http://hdl.handle.net/2152/31031

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