Short synthetic route to taxol and taxol derivatives

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dc.contributor.assigneeBoard of Regents, The University of Texas System
dc.creatorPhilip D. Magnus
dc.date.accessioned2019-10-23T14:31:21Z
dc.date.available2019-10-23T14:31:21Z
dc.date.filed1994-05-24
dc.date.issued1996-04-16
dc.description.abstractA short route to the total synthesis of the core skeleton of the taxol ring system is described. The same sequence of transformations can be carried out to make the 7-hydroxy series, and connect the additional carbon atoms required for the A-ring. The number of steps to the taxane skeleton is 13, making it the shortest route from readily available inexpensive starting materials.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber8248083
dc.identifier.patentnumber5508447
dc.identifier.urihttps://hdl.handle.net/2152/76610
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/3699
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.rights.restrictionOpen
dc.subject.cpcC07D307/42
dc.subject.cpcC07C49/737
dc.subject.cpcC07C49/753
dc.subject.cpcC07D307/93
dc.subject.cpcC07D493/10
dc.subject.uspc549/354
dc.subject.uspc549/214
dc.titleShort synthetic route to taxol and taxol derivatives
dc.typePatent

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