Apoptotic and anti-tumor activities of metallo-salens

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dc.contributor.assigneeBoard of Regents, The University of Texas System
dc.creatorSubhrangsu S. Mandal
dc.creatorKhairul I. Ansari
dc.creatorJames D. Grant, III
dc.date.accessioned2019-10-23T14:02:02Z
dc.date.available2019-10-23T14:02:02Z
dc.date.filed2009-06-24
dc.date.issued2012-06-12
dc.description.abstractThe present invention describes the synthesis and biochemical activities of metallo-salen compounds and their derivatives. The Mn(III)-salen and Fe(III)-salen derivatives of the present invention are potential anti-tumor agents, that affect cell viability, induce strong apoptotic activity, cause nuclear condensation, fragmentation, and ultimately death in breast cancer cells MCF-7.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber12491103
dc.identifier.patentnumber8198322
dc.identifier.urihttps://hdl.handle.net/2152/76381
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/3470
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.rights.restrictionOpen
dc.subject.cpcC07C251/24
dc.subject.uspc514/492
dc.subject.uspc514/502
dc.subject.uspc556/32
dc.titleApoptotic and anti-tumor activities of metallo-salens
dc.typePatent

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