Polarization sensitive optical coherence tomography for primate retinal evaluation in a longitudinal glaucoma study
| dc.contributor.advisor | Rylander, H. Grady (Henry Grady), 1948- | |
| dc.contributor.advisor | Milner, Thomas E. | |
| dc.creator | Dwelle, Jordan Charles | en |
| dc.date.accessioned | 2013-07-08T15:59:21Z | en |
| dc.date.issued | 2011-12 | en |
| dc.date.submitted | December 2011 | en |
| dc.date.updated | 2013-07-08T15:59:21Z | en |
| dc.description | text | en |
| dc.description.abstract | A polarization sensitive optical coherence tomography (PS-OCT) instrument is presented for the study of glaucoma. Glaucoma is the second leading cause of blindness worldwide and causes irreversible damage to the retina. This PS-OCT system was built to perform retinal imaging with a swept source laser providing a 28 kHz A-scan repetition rate. Thickness, phase retardation, birefringence and reflectance index measurements were taken from the primate eyes on a weekly or semi-weekly basis through the course of a 30 week study. Statistical analysis of these measurements indicates that the reflectance index is the earliest measured indicator of glaucomatous changes and a potential marker for early glaucoma diagnosis. | en |
| dc.description.department | Biomedical Engineering | |
| dc.embargo.lift | 12/1/2012 | en |
| dc.embargo.terms | 12/1/2012 | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.uri | http://hdl.handle.net/2152/ETD-UT-2011-12-4709 | en |
| dc.identifier.uri | http://hdl.handle.net/2152/20669 | en |
| dc.language.iso | en_US | en |
| dc.subject | Glaucoma | en |
| dc.subject | Optical coherence tomography | en |
| dc.subject | OCT | en |
| dc.subject | Reflectance | en |
| dc.subject | Retina | en |
| dc.title | Polarization sensitive optical coherence tomography for primate retinal evaluation in a longitudinal glaucoma study | en |
| thesis.degree.department | Biomedical Engineering | en |
| thesis.degree.discipline | Biomedical Engineering | en |
| thesis.degree.grantor | The University of Texas at Austin | en |
| thesis.degree.level | Doctoral | en |
| thesis.degree.name | Doctor of Philosophy | en |