Active-electrode integrated biosensor array and methods for use thereof

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dc.contributor.assigneeBoard of Regents, The University of Texas System
dc.creatorArjang Hassibi
dc.creatorArun Manickam
dc.creatorRituraj Singh
dc.date.accessioned2019-10-23T19:28:41Z
dc.date.available2019-10-23T19:28:41Z
dc.date.filed2013-08-05
dc.date.issued2016-10-11
dc.description.abstractA method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the microwell structure on a surface of a micro-bead, an active electrode or a porous polymer. The device further includes a CMOS-integrated semiconductor integrated circuit, where the CMOS-integrated semiconductor integrated circuit includes metal layers on a silicon substrate, where the metal layers form an active electrode biosensor. In addition, a sensing electrode is formed by creating openings in a passivation layer of the CMOS-integrated semiconductor integrated circuit to hold a single bead, on which the DNA strands are immobilized.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber13959492
dc.identifier.patentnumber9465002
dc.identifier.urihttps://hdl.handle.net/2152/76898
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/3987
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.rights.restrictionOpen
dc.subject.cpcC12Q1/6874
dc.subject.cpcC12Q2535/122
dc.subject.cpcC12Q2565/607
dc.subject.cpcG01N27/27
dc.subject.cpcG01N27/3276
dc.subject.uspcNo longer published
dc.titleActive-electrode integrated biosensor array and methods for use thereof
dc.typePatent

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