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Metal complexes of texaphyrins
(United States Patent and Trademark Office, 1998-09-01)
Texaphyrins are provided for use as radiation sensitizers. Advantageous properties of texaphyrins for use as a radiation sensitizer include: i) a low redox potential which allows radiation-induced hydrated electrons to ...
Rubyrin macrocycles
(United States Patent and Trademark Office, 1997-04-22)
The present invention is directed to the synthesis and use of novel macrocyclic compounds, based upon a new class of expanded porphyrins, termed rubyrins. Disclosed herein is the structure and synthesis of a prototypical ...
Water soluble texaphyrin metal complex preparation
(United States Patent and Trademark Office, 1996-10-29)
The present invention involves water soluble hydroxy-substituted texaphyrins retaining lipophilicity, the synthesis of such compounds and their uses. These expanded porphyrin-like macrocycles are efficient chelators of ...
Reduced sp.sup.3 texaphyrins
(United States Patent and Trademark Office, 1996-04-02)
The present invention involves water soluble hydroxy-substituted texaphyrins retaining lipophilicity, the synthesis of such compounds and their uses. These expanded porphyrin-like macrocycles are efficient chelators of ...
Sapphyrin multimers
(United States Patent and Trademark Office, 1996-12-24)
The present invention provides novel sapphyrin dimers, trimers, oligomers and polymers, which multimers may include repeating units of sapphyrin or sapphyrin derivatives alone, or may further incorporate other units such ...
Water soluble texaphyrin metal complexes for enhancing relaxivity
(United States Patent and Trademark Office, 1995-12-12)
The present invention involves water soluble hydroxy-substituted texaphyrins retaining lipophilicity, the synthesis of such compounds and their uses. These expanded porphyrin-like macrocycles are efficient chelators of ...
Method for separating molecules
(United States Patent and Trademark Office, 1998-04-28)
The present invention provides various novel covalently modified sapphyrin derivatives and conjugates; polymers including sapphyrin or derivatives thereof; and chromatographic supports including sapphyrins and other expanded ...
Water-soluble sapphyrins
(United States Patent and Trademark Office, 1996-08-06)
Sapphyrins are provided having appended functional groups that render the sapphyrin water-soluble. Such water-soluble sapphyrins are useful for photodynamic therapy, for example.
Methods and compositions for treating atheroma, tumors and other neoplastic tissue
(United States Patent and Trademark Office, 2006-09-19)
Injectible formulations comprising motexafin gadolinium are described herein.
Method and compositions for treating atheroma, tumors and other neoplastic tissue
(United States Patent and Trademark Office, 2004-11-30)
The radiation sensitization potential of a candidate compound can be screened by determine its ability to generate one or more reactive oxygen species under appropriate conditions. Compounds determined to have radiation ...