• 1,2-diaminocyclohexane-platinum complexes with antitumor activity 

      Khokhar, Abdul R.; Newman, Robert A. III; Krakoff, Irwin H. (United States Patent and Trademark Office, 1991-04-30)
      The present invention comprises a water-soluble square-planar cis-platinum(II) four-coordinate complex having the formula: EQU trans-R,R-DACH Pt(II) X.sub.2 or EQU trans-R,R-DACH Pt(II) Y wherein X is a monovalvent cation, ...
    • 19F labelled dextrans and antibodies as NMR imaging and spectroscopy agents 

      Kulkarni, Padmakar V.; Antich, Peter P. (United States Patent and Trademark Office, 1993-08-17)
      .sup.19 F labelled compounds are disclosed which are useful in methods of NMR imaging and spectroscopy. The compounds comprise a .sup.19 F-containing sensor moiety, and a transport polymer or substrate, and can optionally ...
    • Abating low-frequency noise using encapsulated gas bubbles 

      Preston S. Wilson; Kevin M. Lee; Mark S. Wochner (United States Patent and Trademark Office, 2014-04-08)
      Air bubbles may be used to reduce radiated underwater noise. Two modalities of sound attenuation by air bubbles were shown to provide a reduction in radiated sound: bubble acoustic resonance damping and acoustic impedance ...
    • Accurately tracking a mobile device to effectively enable mobile device to control another device 

      Wenguang Mao; Lili Qiu (United States Patent and Trademark Office, 2019-01-15)
      A method, system and computer program product for tracking a mobile device. A reference position of the mobile device and a frequency offset between the mobile device and another device are estimated. Samples are then ...
    • Acetic acid as a contrast in reflectance confocal imaging of tissue 

      Rebecca R. Richards-Kortum; Rebekah Drezek; Colin L. Smithpeter; Andres Zuluaga (United States Patent and Trademark Office, 2001-02-13)
      A method for using acetic acid as a contrast agent during reflectance confocal imaging of normal and neoplastic tissue, particularly epithelium. In one aspect, the invention includes a method of using acetic acid as a ...
    • Acidic gas capture by diamines 

      Gary T. Rochelle; Marcus Hilliard (United States Patent and Trademark Office, 2011-05-10)
      Compositions and methods related to the removal of acidic gas. In particular, the present disclosure relates to a composition and method for the removal of acidic gas from a gas mixture using a solvent comprising a diamine ...
    • Acidic gas removal by aqueous amine solvents 

      Gary T. Rochelle; Xi Chen; Stephanie A. Freeman; Thu Nguyen; Alexander Voice; Humera A. Rafique (United States Patent and Trademark Office, 2014-08-26)
      Compositions and methods related to the removal of acidic gas. In one embodiment, compositions and methods are provided for the removal of acidic gas from a gas mixture using an aqueous amine solvent comprising water, a ...
    • Acoustic sensor 

      Neal A. Hall; Michael Louis Kuntzman; Donghwan Kim; Nishshanka Hewa-Kasakarage (United States Patent and Trademark Office, 2016-06-21)
      A method of designing and manufacturing an acoustic sensor having a high degree of directivity is disclosed. The sensor includes a rotatable plate that is attached to a substrate with mounts. In one aspect the mounts are ...
    • Acoustical stimulation of vapor diffusion system and method 

      G. Douglas Meegan, Jr. (United States Patent and Trademark Office, 2007-07-03)
      An apparatus for removing constituents from a fluid stream is provided. The apparatus includes a duct, a collection device, a sorbent injector, and an acoustic generator. The duct has a fluid passageway to receive a fluid ...
    • Active-electrode integrated biosensor array and methods for use thereof 

      Arjang Hassibi; Arun Manickam; Rituraj Singh (United States Patent and Trademark Office, 2016-10-11)
      A method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the ...
    • Active-electrode integrated biosensor array and methods for use thereof 

      Arjang Hassibi; Arun Manickam; Rituraj Singh (United States Patent and Trademark Office, 2016-05-17)
      A method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the ...
    • Adaptive feedback method for cellular communication 

      Sung Hyun Cho; Robert W. Heath, Jr.; Sang-Boh Yun; Taiwen Tang (United States Patent and Trademark Office, 2010-04-06)
      In an adaptive feedback method for a cellular communication system having plural terminals feeding back channel information to an access point, the system selects one of an opportunistic mode and a polling mode as a feedback ...
    • Adaptive nanotopography sculpting 

      Sidlgata V. Sreenivasan; Avinash Panga (United States Patent and Trademark Office, 2013-03-12)
      Adaptive imprint planarization provides a surface having desired shape characteristics. Generally, topography of a first surface is mapped to provide a density map. The density map is evaluated to provide a drop pattern ...
    • Adaptive shape substrate support method 

      Mahadevan GanapathiSubramanian; Sldlgata V. Sreenivasan (United States Patent and Trademark Office, 2009-03-17)
      The present method features an active compliant pin chuck to hold a substrate, having opposed first and second surfaces, and compensates for non-planarity in one of the surfaces of the substrate. To that end, the method ...
    • Adaptive shape substrate support system 

      Sidlgata V. Sreenivasan; Mahadevan GanapathiSubramanian (United States Patent and Trademark Office, 2007-12-11)
      The present method and system features an active compliant pin chuck to hold a substrate, having opposed first and second surfaces, and compensates for non-planarity in one of the surfaces of the substrate. To that end, ...
    • Administration of kynurenine depleting enzymes for tumor therapy 

      George M. Georgiou; Everett Stone (United States Patent and Trademark Office, 2017-11-07)
      Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, ...
    • Administration of kynurenine depleting enzymes for tumor therapy 

      George M. Georgiou; Everett Stone; Wei-Cheng Lu; John Blazeck; Nicholas Marshall (United States Patent and Trademark Office, 2018-05-22)
      Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, ...
    • Admittance measurement for tuning bi-ventricular pacemakers 

      Marc D. Feldman; Jonathan W. Valvano; John A. Pearce; John R. Porterfield; Erik Steven Larson (United States Patent and Trademark Office, 2018-09-18)
      An apparatus for treating a heart of a patient includes a first lead and at least a second lead for pacing the heart adapted to be in electrical communication with the heart. The apparatus includes a microcontroller in ...
    • Aerosol jet etching 

      James R. Brock; Isaac Trachtenberg (United States Patent and Trademark Office, 1991-08-20)
      A device and method for etching a body are provided capable of etching fine geometry patterns utilizing the high selectivity of wet etching and the anisotropic etch characteristics of dry etching. The body to be etched is ...
    • Aerosol-mediated particle synthesis 

      Hugh D. Smyth; Ibrahim M. El-Sherbiny (United States Patent and Trademark Office, 2014-02-18)
      Disclosed are aerosol-mediated methods for synthesizing particles for biomedical and drug delivery applications. The method is based on the production of particles from sprayed polymeric micro or nano-droplets obtained by, ...