Membrane Adhesion and the Formation of Heterogeneities: Biology, Biophysics, and Biotechnology

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Gordon, Vernita D.
O'Halloran, T. J.
Shindell, O.

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Physical Chemistry Chemical Physics


Membrane adhesion is essential to many vital biological processes. Sites of membrane adhesion are often associated with heterogeneities in the lipid and protein composition of the membrane. These heterogeneities are thought to play functional roles by facilitating interactions between proteins. However, the causal links between membrane adhesion and membrane heterogeneities are not known. Here we survey the state of the field and indicate what we think are understudied areas ripe for development.


a. The University of Texas at Austin, Department of Physics and Center for Nonlinear Dynamics, 2515 Speedway, Stop C1610, Austin, Texas 78712-1199, USA. E-mail: b.The University of Texas at Austin, Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Austin, Texas 78712-1199, USA

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Gordon, V. D., T. J. O'Halloran, and O. Shindell. "Membrane adhesion and the formation of heterogeneities: biology, biophysics, and biotechnology." Physical Chemistry Chemical Physics 17, no. 24 (2015): 15522-15533.