Precision Extrusion Deposition of Polycaprolactone/Hydroxyapatite Tissue Scaffolds

Access full-text files

Date

2006

Authors

Shor, L.
Güçeri, S.
Sun, W.

Journal Title

Journal ISSN

Volume Title

Publisher

Abstract

Freeform fabrication provides an effective process tool to manufacture advanced tissue scaffolds with specific designed properties. Our research focuses on using a novel Precision Extrusion Deposition (PED) process technique to directly fabricate Polycaprolactone (PCL) and composite PCL/ Hydroxyapatite (HA) tissue scaffolds. The scaffold morphology and the mechanical properties were evaluated using SEM and mechanical testing. In vitro biological studies were conducted to investigate the cellular responses of the composite scaffolds. Results and characterizations demonstrate the viability of the PED process as well as the good mechanical property, structural integrity, controlled pore size, pore interconnectivity, and the biological compatibility of the fabricated scaffolds.

Description

LCSH Subject Headings

Citation