First results from the Time-of-Flight PET for proton therapy

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2023-08

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There is a clear and distinct need in the field of proton and ion radio-therapies to accurately monitor the location of the Bragg Peak produced by the therapy in the patient. To this end, the Time-of-Flight PET for Proton Therapy (TPPT) consortium has constructed and partially commissioned an in-line Positron Emission Tomography (PET) scanner to monitor the activity of Positron Emitting Species (PES) produced as a result of Proton Beam interactions within the patient. The scanner has a timing resolution near 200 picoseconds that will allow it to successfully reconstruct an image of PES activity to ensure the proton beam is not depositing significant amounts of energy in healthy tissue. First, the motivation behind the scanner is discussed, then the components of the scanner and their capabilities are described. The commissioning process of the scanner is detailed and finally some preliminary results in the form of reconstructed images and next steps for the consortium are discussed.

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