Targeting proteins to deliver therapeutic or diagnostic reagents
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Date
2011-03-15
Authors
Lan, Keng-Hsin
Hung, Mien-Chie
Liu, Jaw-Ching
Yang, Fu Ou
Journal Title
Journal ISSN
Volume Title
Publisher
United States Patent and Trademark Office
Abstract
The present invention is directed to compositions comprising an angiogenesis inhibitor coupled to a therapeutic or diagnostic agent. In a specific embodiment, the composition is a fusion gene or fusion gene product encoding the angiogenesis inhibitor coupled to a therapeutic or diagnostic agent. In a particular embodiment, the composition is used for methods to treat angiogenesis-related diseases, such as cancer.