Biodegradable scaffolds

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dc.contributor.assigneeThe Board of Regents of the University of Texas System
dc.creatorRachel Buchanan
dc.creatorChristine Smid
dc.creatorMauro Ferrari
dc.creatorEnnio Tasciotti
dc.date.accessioned2019-10-23T19:32:46Z
dc.date.available2019-10-23T19:32:46Z
dc.date.filed2016-09-20
dc.date.issued2018-08-28
dc.description.abstractIn some embodiments, the present invention provides compositions that comprise: (1) a biodegradable polymer matrix; and (2) at least one biodegradable reinforcing particle that is dispersed in the matrix. In some embodiments, the biodegradable reinforcing particle is selected from the group consisting of porous oxide particles and porous semiconductor particles. In additional embodiments, the compositions of the present invention further comprise a (3) porogen particle that is also dispersed in the matrix. In further embodiments, the compositions of the present invention are also associated with one or more active agents. In various embodiments, the active agents are associated with the biodegradable polymer matrix, the biodegradable reinforcing particle, and/or the porogen particle. In various embodiments, the compositions of the present invention may be utilized as scaffolds, such as scaffolds for treating bone defects. Further embodiments of the present invention pertain to methods of making the compositions of the present invention.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber15270324
dc.identifier.patentnumber10058633
dc.identifier.urihttps://hdl.handle.net/2152/77098
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/4187
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.rights.restrictionOpen
dc.subject.cpcA61L27/56
dc.subject.cpcA61L27/16
dc.subject.cpcA61L27/18
dc.subject.cpcA61L27/20
dc.subject.cpcA61L27/3834
dc.subject.cpcA61L27/3847
dc.subject.cpcA61L27/446
dc.subject.cpcA61L27/54
dc.subject.cpcA61L27/58
dc.subject.cpcA61L2300/252
dc.subject.cpcA61L2300/406
dc.subject.cpcA61L2300/41
dc.subject.cpcA61L2300/44
dc.subject.cpcA61L2300/64
dc.subject.cpcA61L2430/02
dc.titleBiodegradable scaffolds
dc.typePatent

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