Method of cleaving DNA

dc.contributor.assigneeThe Board of Regents of the University of Texas System
dc.creatorRichard E. Thomas
dc.creatorJonathan L. Sessler
dc.creatorBrent L. Iverson
dc.creatorVladimir A. Kral
dc.creatorKevin Shreder
dc.creatorHiroyuki Furuta
dc.date.accessioned2019-10-23T19:32:50Z
dc.date.available2019-10-23T19:32:50Z
dc.date.filed1995-06-02
dc.date.issued1997-09-30
dc.description.abstractThe present invention provides various novel covalently modified sapphyrin derivatives and conjugates; polymers including sapphyrin or derivatives thereof; and chromatographic supports including sapphyrins and other expanded porphyrins and derivatives thereof. Disclosed are water soluble sapphyrins, including polyhydroxysapphyrins and sapphyrin-sugar derivatives; sapphyrin-metal chelating conjugates; sapphyrin nucleobase conjugates; oligosapphyrins and polysapphyrins, including sapphyrin dimers, trimers, oligomers and higher polymers; and polymer supported expanded porphyrin compositions, including advantageous rubyrin- and sapphyrin-based chromatography columns and electrophoretic supports. Sapphyrin oligomers and polymers and polymer supported expanded porphyrins, such as, e.g., glass and silica expanded porphyrin constructs, are disclosed which include both repeating units of sapphyrin derivatives alone and which include other units, for example, nucleobases, sapphyrin-nucleobase conjugates and long chain alkyl groups.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber8460669
dc.identifier.patentnumber5672490
dc.identifier.urihttps://hdl.handle.net/2152/77107
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/4196
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.rights.restrictionOpen
dc.subject.cpcA61K41/0076
dc.subject.cpcA61K47/54
dc.subject.cpcA61K47/546
dc.subject.cpcA61K47/558
dc.subject.cpcC07H21/00
dc.subject.cpcC07D487/22
dc.subject.cpcC07H15/26
dc.subject.cpcC12N15/101
dc.subject.uspc435/91.1
dc.subject.uspc540/472
dc.titleMethod of cleaving DNA
dc.typePatent

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