Resistance training as a modality to enhance muscle regeneration in a rat skeletal muscle defect

dc.contributor.advisorFarrar, Roger P.en
dc.contributor.committeeMemberSuggs, Lauraen
dc.creatorTaylor, Daniel Ryanen
dc.date.accessioned2010-08-25T14:09:44Zen
dc.date.available2010-08-25T14:09:44Zen
dc.date.available2010-08-25T14:09:50Zen
dc.date.issued2009-12en
dc.date.submittedDecember 2009en
dc.date.updated2010-08-25T14:09:50Zen
dc.descriptiontexten
dc.description.abstractTraumatic skeletal muscle injuries that include loss of large amounts of muscle mass are becoming more common in today’s warfare. Traditional treatments often do not prevent long term functional impairments. Using a decellularized extracellular matrix (ECM) as scaffolding to replace lost muscle tissue allows for transmission of force through the injury site, and provides a suitable microenvironment receptive to myofiber growth. Seeding the ECM with progenitor cells improves cellular content in the defect area. Exercise exposes the muscle to improved blood flow as well as higher than normal loading. This results in increased blood vessel density as well as higher levels of cellular content, and near complete restoration of function.en
dc.description.departmentKinesiology and Health Education
dc.format.mimetypeapplication/pdfen
dc.identifier.urihttp://hdl.handle.net/2152/ETD-UT-2009-12-612en
dc.language.isoengen
dc.subjectMuscleen
dc.subjectRegenerationen
dc.subjectExtracellular matrixen
dc.subjectStem cellsen
dc.subjectExerciseen
dc.subjectResistance trainingen
dc.subjectDefecten
dc.titleResistance training as a modality to enhance muscle regeneration in a rat skeletal muscle defecten
dc.type.genrethesisen
thesis.degree.departmentKinesiology and Health Educationen
thesis.degree.disciplineKinesiologyen
thesis.degree.grantorThe University of Texas at Austinen
thesis.degree.levelMastersen
thesis.degree.nameMaster of Artsen

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