Hybrid cell lines producing monoclonal antibodies directed against Treponema

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Date

1985-04-30

Authors

Kettman, John R.
Norgard, Michael V.

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United States Patent and Trademark Office

Abstract

Continuous hybrid cell lines for producing monoclonal antibodies directed against antigens of Treponema pallidum have been developed. The hybrid cell lines were established by fusing differentiated lymphoid cells primed with antigens of Treponema pallidum with hybridoma cells. The resulting fused cells were cloned, isolated, cultured and characterized as to antibody specificity against antigenic determinants of Treponema pallidum.

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