Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems

Date
2012-01-24
Authors
Dean P. Neikirk
Jason B. Shear
John T. McDevitt
Eric V. Anslyn
Karri L. Ballard
Nick J. Christodoulides
Pierre N. Floriano
Journal Title
Journal ISSN
Volume Title
Publisher
United States Patent and Trademark Office
Abstract

Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.

Description
Keywords
Citation