Selection method for cell internalizing nucleic acids

Date
2012-10-30
Authors
Andrew D. Ellington
Matthew Levy
Amy Yan
Ted Chitai Chu
Journal Title
Journal ISSN
Volume Title
Publisher
United States Patent and Trademark Office
Abstract

The present invention includes compositions and methods for contacting one or more cells with a random RNA-containing library, treating the contacted cells and with a denaturing agent or digestion with one or more nucleases, and extracting from the cells one or more internalized nucleic acids resistant to the nucleases or denaturants.

Description
Keywords
Citation