Systems, devices, and methods for optically clearing tissue

dc.contributor.assigneeBoard of Regents, The University of Texas System
dc.creatorMilner, Thomas E.
dc.creatorNelson, J. Stuart
dc.creatorRylander, Christopher G.
dc.creatorStumpp, Oliver
dc.date.accessioned2019-10-23T14:01:51Z
dc.date.available2019-10-23T14:01:51Z
dc.date.filed2006-08-12
dc.date.issued2012-12-04
dc.description.abstractEmbodiments of the present disclosure provides systems, devices, and methods for non-invasively modifying, maintaining, or controlling local tissue optical properties. Methods and devices of the disclosure may be used for optically clearing tissue, for example, for diagnostic and/or therapeutic purposes. A method of optically clearing a tissue may comprise contacting the tissue with an optical clearing device having a base, an array of pins fixed to one side of the base, a brim fixed to the base, an inlet port in the base, an exit port in the base, and a handpiece interface tab fixed to the side of the base opposite the array of pins, applying a mechanical force to the tissue, and illuminating said tissue with at least one wavelength of light through the optical clearing device. A method may further comprise controlling the temperature of the tissue illuminated.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber11502687
dc.identifier.patentnumber8323273
dc.identifier.urihttps://hdl.handle.net/2152/76364
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/3453
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.rights.restrictionOpen
dc.subject.cpcA61N5/06
dc.subject.cpcA61B5/0066
dc.subject.cpcA61B5/0068
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dc.subject.cpcA61B18/14
dc.subject.cpcA61B18/1815
dc.subject.cpcA61B2017/306
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dc.subject.cpcA61B2018/00035
dc.subject.cpcA61B2018/00452
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dc.subject.cpcA61N2005/063
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dc.subject.uspc606/9
dc.subject.uspc607/88
dc.subject.uspc607/89
dc.titleSystems, devices, and methods for optically clearing tissue
dc.typePatent

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