Method of identifying inhibitors of glutathione S-transferase (GST) gene expression

dc.contributor.assigneeThe University of Mississippi
dc.contributor.assigneeBoard of Regents, Univ. of Tex. Sys.
dc.creatorLopez-Berestein, Gabriel
dc.creatorBuolamwini, John K.
dc.creatorKeller, Charles W.
dc.creatorAli-Osman, Francis
dc.creatorAntoun, Gamil
dc.creatorLo, Hui-Wen
dc.creatorAkande, Olanike
dc.date.accessioned2019-05-14T14:34:53Z
dc.date.available2019-05-14T14:34:53Z
dc.date.filed1999-10-19
dc.date.issued1999-10-19
dc.description.abstractComplementary DNA and genomic clones for three variants of GST-.pi. are disclosed. It is demonstrated that certain of these variants are overexpressed in gliomas, thereby indicating an involvement with that form of cancer. This permits the detection and treatment of certain classes of tumors using new compositions such as GST-.pi. genes, oligonucleotides, peptides and antibodies.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber8747536
dc.identifier.patentnumber5968737
dc.identifier.urihttps://hdl.handle.net/2152/74677
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/1795
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.subject.cpcC12Q1/48
dc.subject.cpcG01N33/5011
dc.subject.cpcG01N33/57484
dc.subject.uspc435/6.14
dc.subject.uspc435/15
dc.subject.uspc435/91.31
dc.subject.uspc435/193
dc.subject.uspc435/375
dc.subject.uspc536/24.5
dc.titleMethod of identifying inhibitors of glutathione S-transferase (GST) gene expression
dc.typePatent

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