A direct, concise and stereoselective formal synthesis of platensimycin

dc.contributor.advisorMagnus, Philip D.en
dc.contributor.committeeMemberKrische, Michael J.en
dc.contributor.committeeMemberJones, Richard M.en
dc.contributor.committeeMemberSiegel, Dionicio R.en
dc.contributor.committeeMemberKerwin, Sean M.en
dc.creatorRivera, Heribertoen
dc.date.accessioned2012-01-27T21:25:35Zen
dc.date.available2012-01-27T21:25:35Zen
dc.date.issued2011-12en
dc.date.submittedDecember 2011en
dc.date.updated2012-01-27T21:25:48Zen
dc.descriptiontexten
dc.description.abstractHerein we describe the synthesis of (±) platensimycin, a potent antibiotic against gram-positive bacteria. The first chapter reviews (±) platensimycin’s isolation, biological profile and previously reported studies relevant to the area. The second chapter describes our initial efforts to synthesize (±) platensimycin. The third chapter accounts our second generation synthesis and its completion. The fourth chapter entails the experimental details of the important compounds in our synthesis.en
dc.description.departmentChemistryen
dc.format.mimetypeapplication/pdfen
dc.identifier.slug2152/ETD-UT-2011-12-4421en
dc.identifier.urihttp://hdl.handle.net/2152/ETD-UT-2011-12-4421en
dc.language.isoengen
dc.subjectPlatensimycinen
dc.subjectSynthesisen
dc.subjectAntibioticen
dc.titleA direct, concise and stereoselective formal synthesis of platensimycinen
dc.type.genrethesisen
thesis.degree.departmentChemistryen
thesis.degree.disciplineChemistryen
thesis.degree.grantorUniversity of Texas at Austinen
thesis.degree.levelDoctoralen
thesis.degree.nameDoctor of Philosophyen

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