BK channel-modulating peptides and their use

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Date

2019-01-22

Authors

Luisa Lynn Scott
Joseph Paul Walton

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United States Patent and Trademark Office

Abstract

The present invention concerns peptides and nucleic acids encoding the peptides, and their use for modulating large conductance Ca2+ activated K+ (BK) channel activity in cells; for treating conditions such as presbycusis (age-related hearing loss), audiogenic seizures, alcohol addiction, cancer, and neurodegenerative disease; and for delivering a cargo moiety to the brain of a subject through the blood-brain barrier.

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