Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair

dc.contributor.assigneeBoard of Regents, Univ. of Tex. Sys.
dc.creatorOlson, Eric N.
dc.creatorvan Rooij, Eva
dc.date.accessioned2019-05-14T14:33:06Z
dc.date.available2019-05-14T14:33:06Z
dc.date.filed2015-07-14
dc.date.issued2015-07-14
dc.description.abstractA family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, with consequent loss of cardiomyocytes. Strategies to block expression of the miR-15 family in the heart as a treatment for diverse cardiac disease are provided.
dc.description.departmentBoard of Regents, University of Texas System
dc.identifier.applicationnumber13970379
dc.identifier.patentnumber9078919
dc.identifier.urihttps://hdl.handle.net/2152/74579
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/1697
dc.publisherUnited States Patent and Trademark Office
dc.relation.ispartofUniversity of Texas Patents
dc.rights.restrictionOpen
dc.subject.cpcA01K67/0275
dc.subject.cpcA01K2207/05
dc.subject.cpcA01K2217/058
dc.subject.cpcA01K2227/105
dc.subject.cpcA01K2267/0375
dc.subject.cpcA61K45/06
dc.subject.cpcA61K31/7105
dc.subject.cpcC12N15/113
dc.subject.cpcC12N2310/113
dc.subject.cpcC12N2310/14
dc.subject.cpcC12N2330/10
dc.subject.cpcC12N2830/008
dc.titleMicro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair
dc.typePatent

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