The effect of the menstrual cycle on hemoglobin mass

dc.contributor.advisorLalande, Sophie
dc.creatorKeller, Melissa Faith
dc.creator.orcid0000-0003-3404-3685
dc.date.accessioned2019-10-16T22:41:21Z
dc.date.available2019-10-16T22:41:21Z
dc.date.created2019-05
dc.date.issued2019-05-08
dc.date.submittedMay 2019
dc.date.updated2019-10-16T22:41:21Z
dc.description.abstractThe impact of the menstrual cycle on oxygen-carrying capacity remains equivocal. Previous studies reported either reductions or no significant changes in hemoglobin concentration during the follicular phase when compared to the luteal phase of the menstrual cycle. Changes in plasma volume associated with fluctuating estrogen and progesterone levels likely contribute to the variations in hemoglobin concentration observed throughout the menstrual cycle. Thus, measures of hemoglobin concentration do not accurately represent the oxygen-carrying capacity of the blood. Hemoglobin mass represents a more direct measure of oxygen-carrying capacity. However, the impact of menstrual blood loss on hemoglobin mass remains unknown. PURPOSE: To determine the effect of the menstrual cycle on hemoglobin mass in pre-menopausal women. METHODS: Twenty-one women (age: 23 ± 6 years, height: 167 ± 7 cm, weight: 66 ± 13 kg) with a regular menstrual cycle using (n = 9) and not using hormonal contraceptives participated in the study. Hemoglobin mass was assessed using the carbon monoxide rebreathing technique on three separate occasions. Visits for women using hormonal contraceptives were scheduled in the early follicular phase (3-5 days post-onset of menses), late follicular phase (14 days post-onset of menses), and mid-to-late luteal phase (10 days after the late follicular visit). Visits for women not using hormonal contraceptives were scheduled in the early follicular phase (3-5 days post-onset of menses), late follicular phase (1-2 days post-surge of luteinizing hormone in urine), and mid-to-late luteal phase (10 days after the late follicular visit). RESULTS: No differences were observed in hemoglobin concentration across phases of the menstrual cycle (early follicular: 12.9 ± 1.3 g/dl, late follicular: 12.7 ± 0.9 g/dl, mid-to-late luteal: 12.8 ± 0.9 g/dl, p = 0.08). Likewise, hemoglobin mass did not significantly differ between menstrual cycle phases (early follicular: 606 ± 73 g, late follicular: 602 ± 73 g, mid-to-late luteal: 606 ± 68 g, p = 0.90). Hemoglobin mass for women using hormonal contraceptive tended to be higher than non-users across the menstrual cycle (early follicular: 629 ± 53 g vs. 590 ± 83 g, late follicular: 635 ± 58 g vs. 577 ± 75 g, mid-to-late luteal: 626 ± 61 vs. 592 ± 71 g, respectively, p = 0.12). CONCLUSION: The menstrual cycle has no significant impact on hemoglobin mass or oxygen-carrying capacity in eumenorrheic women. The use of hormonal contraceptives may improve oxygen-carrying capacity.
dc.description.departmentKinesiology and Health Education
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/2152/76215
dc.identifier.urihttp://dx.doi.org/10.26153/tsw/3304
dc.language.isoen
dc.subjectOxygen-carrying capacity
dc.subjectBlood volume
dc.subjectEarly follicular phase
dc.subjectEstrogen
dc.subjectProgesterone
dc.titleThe effect of the menstrual cycle on hemoglobin mass
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentKinesiology and Health Education
thesis.degree.disciplineKinesiology
thesis.degree.grantorThe University of Texas at Austin
thesis.degree.levelMasters
thesis.degree.nameMaster of Science in Kinesiology
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
KELLER-THESIS-2019.pdf
Size:
482.43 KB
Format:
Adobe Portable Document Format
License bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
PROQUEST_LICENSE.txt
Size:
4.45 KB
Format:
Plain Text
Description:
No Thumbnail Available
Name:
LICENSE.txt
Size:
1.84 KB
Format:
Plain Text
Description: