SLS Fabrication of Highly Porous Model Including Fine Flow Channel Network Aiming at Regeneration of Highly Metabolic Organs
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Date
2006-09-14
Authors
Niino, Toshiki
Sakai, Yasuyuki
Huang, Hongyun
Naruke, Hiromichi
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Abstract
Fabrication of very porous scaffold for regeneration of highly metabolic organs is reported. Polycaprolactone (PCL) powder was mixed with fine salt grains as filler and SLS processed to develop a model including fine flow channel network. The fabricated model was rinsed with water to dissolve the salt, and high porosity of 90% was successfully obtained. Additionally, residual powder in the channels was effectively removed by solution of the filler. Through micro-CT observation, it was confirmed that channels of which diameter was smaller than 1mm were successfully fabricated and repeating branching and merging. Result of culture test is also reported.