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    Chemoprevention of electrophilic damage by mercaptopurine analogs

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    US5120753.pdf (891.0Kb)
    Date
    1992-06-09
    Author
    Michael C. MacLeod
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    Abstract
    Analogs of 6-mercaptopurine have been found to enhance the detoxification of various electrophilic toxicants in vivo, while having minimal cytotoxicity themselves. This property allows such compounds to act as scavengers for electrophilic toxicants, thereby preventing the cellular damage caused by such toxic agents.
    Department
    Board of Regents, University of Texas System
    URI
    https://hdl.handle.net/2152/77373
    http://dx.doi.org/10.26153/tsw/4462
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