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Thermo-kinetic mixing for pharmaceutical applications
(United States Patent and Trademark Office, 2016-05-17)
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable ...
Stabilized HME composition with small drug particles
(United States Patent and Trademark Office, 2016-11-29)
A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does ...
Enhanced delivery of drug compositions to treat life threatening infections
(United States Patent and Trademark Office, 2015-06-23)
Inhalable compositions are described. The inhalable compositions comprise one or more respirable aggregates, the respirable aggregates comprising one or more poorly water soluble active agents, wherein at least one of the ...
Stabilized HME composition with small drug particles
(United States Patent and Trademark Office, 2017-08-15)
A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does ...
Methods for fine particle manufacture
(United States Patent and Trademark Office, 2016-06-21)
Processes for preparing micronized particles comprising a poorly water soluble bioactive agent are provided. The processes utilize a superheated aqueous phase which can serve as the continuous phase of an emulsion. The ...
Enhanced delivery of drug compositions to treat life threatening infections
(United States Patent and Trademark Office, 2017-08-08)
Inhalable compositions are described. The inhalable compositions comprise one or more respirable aggregates, the respirable aggregates comprising one or more poorly water soluble active agents, wherein at least one of the ...