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Hot-melt extrusion of modified release multi-particulates
(United States Patent and Trademark Office, 2015-11-24)
The present invention includes compositions and methods of making a modified release pharmaceutical formulation and a method of preparation for the embedding of modified release multi-particulates into a polymeric or ...
Formation of stable submicron peptide or protein particles by thin film freezing
(United States Patent and Trademark Office, 2017-04-18)
The present invention includes compositions and methods for preparing micron-sized or submicron-sized particles by dissolving a water soluble effective ingredient in one or more solvents; spraying or dripping droplets ...
Hemoglobin contrast in magneto-motive optical doppler tomography, optical coherence tomography, and ultrasound imaging methods and apparatus
(United States Patent and Trademark Office, 2013-01-15)
Provided herein are systems, methods, and compositions for the use of optical coherence tomography for detection of cells.
Photopolymerizable compositions for solventless fiber spinning
(United States Patent and Trademark Office, 2019-03-05)
Disclosed are methods of fiber spinning and polymer fibers that utilize multifunctional thiol and enes compounds. Also, the subject matter disclosed herein relates to uses of polymer fibers and articles prepared from such fibers.
Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair
(United States Patent and Trademark Office, 2015-07-14)
A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, ...
Methods and compositions to reduce scattering of light during therapeutic and diagnostic imaging procedures
(United States Patent and Trademark Office, 2011-07-19)
Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment ...
System and method for pump with deformable bearing surface
(United States Patent and Trademark Office, 2012-05-01)
Systems and methods for pumping fluid comprising a pumping chamber, a pump inlet, a pump outlet, a valving mechanism, and a drive piston or pumping chamber wall including a deformable surface configured to provide ...
Controlled release nanoparticulate matter delivery system
(United States Patent and Trademark Office, 2016-12-20)
A controlled release nanoparticulate matter delivery system includes a plurality of thermoresponsive modules containing a respective nanoparticulate matter. Each thermoresponsive module is selectively operable in at least ...
Inorganic nanowires
(United States Patent and Trademark Office, 2012-06-19)
An inorganic nanowire having an organic scaffold substantially removed from the inorganic nanowire, the inorganic nanowire consisting essentially of fused inorganic nanoparticles substantially free of the organic scaffold, ...
Incorporating CMOS integrated circuits in the design of affinity-based biosensor systems
(United States Patent and Trademark Office, 2013-08-27)
A biosensor system incorporating CMOS integrated circuits. In one type of biosensor system, the biosensor system includes a silicon substrate. The biosensor system further includes active devices fabricated on the silicon ...