Now showing items 1-10 of 39
(United States Patent and Trademark Office, 1998-09-15)
The invention relates to the field of polymer- and other matrix-supported sapphyrins. Disclosed are silica gel, glass, resin and other polymer- and matrix-supported sapphyrins and sapphyrin-containing chromatographic and ...
Phosphoramidite derivatives of macrocycles
(United States Patent and Trademark Office, 1998-11-17)
The invention is directed to phosphoramidite derivatives of macrocycles, such as porphyrins and expanded porphyrins, including sapphyrins and texaphyrins. The phosphoramidite derivatives are useful as intermediates in the ...
Texaphyrin solid supports and devices
(United States Patent and Trademark Office, 1997-01-14)
The present invention provides various novel matrix-supported texaphyrins in which a polymeric or solid matrix is covalently modified by the addition of one or more texaphyrins or texaphyrin derivatives. Described are ...
Texaphyrin compounds having improved functionalization
(United States Patent and Trademark Office, 1997-02-04)
Texaphyrin metal complexes having improved functionalization include the addition of electron-donating groups to positions 2, 7, 12, 15, 18 and/or 21 and/or the addition of electron-withdrawing groups to positions 15 and/or ...
Rubyrin and related expanded porphyrins
(United States Patent and Trademark Office, 1995-04-25)
The present invention is directed to the synthesis and use of novel macrocyclic compounds, based upon a new class of expanded porphyrins, termed rubyrins. Disclosed herein is the structure and synthesis of a prototypical ...
Membrane incorporation of texaphyrins
(United States Patent and Trademark Office, 2002-04-23)
Compositions having a texaphyrin-lipophilic molecule conjugate loaded into a biological vesicle and methods for imaging, diagnosis and treatment using the loaded vesicle are provided. For example, liposomes or red blood ...
Porphyrin compounds as telomerase inhibitors
(United States Patent and Trademark Office, 2000-07-11)
The present invention has identified compounds with extended aromatic chromophores that bind the G-quadruplex formed by the folding of single-stranded human telomeric DNA. These compounds have been shown to be effective ...
Metal complexes of water soluble texaphyrins
(United States Patent and Trademark Office, 1993-10-12)
Texaphyrin macrocycles and metal complexes thereof
(United States Patent and Trademark Office, 1996-12-24)
" The present invention involves a novel tripyrrole dimethine-derived ""expanded porphyrin"" (texaphyrin), the synthesis of such compounds, their analogs or derivatives and their uses. These expanded porphyrin-like macrocycles ...
(United States Patent and Trademark Office, 1995-10-10)
A method of using texaphyrins as radiosensitizers. Advantageous properties of texaphyrins for use as a radiosensitizer include i) a low redox potential which allows radiation induced solvated electrons to flow to texaphyrin ...