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Membrane incorporation of texaphyrins
(United States Patent and Trademark Office, 2002-04-23)
Compositions having a texaphyrin-lipophilic molecule conjugate loaded into a biological vesicle and methods for imaging, diagnosis and treatment using the loaded vesicle are provided. For example, liposomes or red blood ...
Porphyrin compounds as telomerase inhibitors
(United States Patent and Trademark Office, 2000-07-11)
The present invention has identified compounds with extended aromatic chromophores that bind the G-quadruplex formed by the folding of single-stranded human telomeric DNA. These compounds have been shown to be effective ...
Methods and compositions for treating atheroma, tumors and other neoplastic tissue
(United States Patent and Trademark Office, 2006-09-19)
Injectible formulations comprising motexafin gadolinium are described herein.
Method and compositions for treating atheroma, tumors and other neoplastic tissue
(United States Patent and Trademark Office, 2004-11-30)
The radiation sensitization potential of a candidate compound can be screened by determine its ability to generate one or more reactive oxygen species under appropriate conditions. Compounds determined to have radiation ...
Halogenated calixpyrroles and uses thereof
(United States Patent and Trademark Office, 2006-05-09)
The present invention provides halogenated calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles having 4–12 pyrrolic rings with greater stability, enhanced anion and neutral molecule binding affinity, and ...
Calixpyrroles, calixpyridinopyrroles and calixpyridines
(United States Patent and Trademark Office, 2001-07-17)
The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports ...
Calixpyrroles
(United States Patent and Trademark Office, 2006-10-17)
The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports ...
Conjugates of texaphyrins
(United States Patent and Trademark Office, 2000-06-06)
The invention relates to the field of radiation sensitizers and the use of texaphyrins for radiation sensitization and other conditions for which X-ray radiation has proven to be therapeutic.