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Methods of treating cancer comprising targeting NQO1
(United States Patent and Trademark Office, 2016-10-18)
Disclosed herein are methods for determining whether an individual with cancer is suitable for a treatment with an NQO1 bioactivatable drug, predicting responsiveness of an individual with cancer to a treatment with an ...
Calcium formate as a supplement to prevent neural tube defects
(United States Patent and Trademark Office, 2018-02-20)
Compositions and method for treating a folate-resistant disease in a subject are disclosed. The methods involve administering to the subject an effective amount of a composition containing a formate. For example, the method ...
Nitrite formulations and their use as nitric oxide prodrugs
(United States Patent and Trademark Office, 2015-09-01)
Compositions comprising from about 40 weight parts to about 1000 weight parts of a botanical nitrate source; from about 20 weight parts to about 500 weight parts of a botanical source of nitrite reduction activity; and ...
Engineered primate L-methioninase for therapeutic purposes
(United States Patent and Trademark Office, 2016-11-01)
Methods and compositions relating to the engineering of an improved protein with methionine-γ-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase ...
Engineered primate L-methioninase for therapeutic purposes
(United States Patent and Trademark Office, 2017-04-18)
Methods and compositions relating to the engineering of an improved protein with methionine-γ-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase ...
Compositions and methods for treating cancer
(United States Patent and Trademark Office, 2015-07-07)
Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression.