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    Formation of stable submicron peptide or protein particles by thin film freezing 

    Robert O. Williams, III; Keith P. Johnston; Joshua Engstrom (United States Patent and Trademark Office, 2017-04-18)
    The present invention includes compositions and methods for preparing micron-sized or submicron-sized particles by dissolving a water soluble effective ingredient in one or more solvents; spraying or dripping droplets ...
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    Thermo-kinetic mixing for pharmaceutical applications 

    Robert O. Williams, III; James W. McGinity; Chris Brough; Dave A. Miller; James C. DiNunzio (United States Patent and Trademark Office, 2016-05-17)
    Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable ...
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    Stabilized HME composition with small drug particles 

    Robert O. Williams, III; James W. McGinity; Dave A. Miller; Jason T. McConville (United States Patent and Trademark Office, 2016-11-29)
    A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does ...
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    Enhanced delivery of drug compositions to treat life threatening infections 

    Robert O. Williams, III; Christopher J. Tucker; Keith P. Johnston; James E. Hitt; Brian D. Scherzer; Timothy J. Young; True L. Rogers; David A. Hayes; David S. Burgess; Jason T. McConville; Robert Talbert; Jay I. Peters; Ian B. Gillespie; Paula C. Garcia; Nicholas S. Beck (United States Patent and Trademark Office, 2015-06-23)
    Inhalable compositions are described. The inhalable compositions comprise one or more respirable aggregates, the respirable aggregates comprising one or more poorly water soluble active agents, wherein at least one of the ...
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    Stabilized HME composition with small drug particles 

    Robert O. Williams, III; James W. McGinity; Dave A. Miller; Jason T. McConville (United States Patent and Trademark Office, 2017-08-15)
    A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does ...
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    Enhanced delivery of drug compositions to treat life threatening infections 

    Robert O. Williams, III; Christopher J. Tucker; Keith P. Johnston; James E. Hitt; Brian D. Scherzer; Timothy J. Young; True L. Rogers; David A. Hayes; David S. Burgess; Jason T. McConville; Robert Talbert; Jay I. Peters; Ian B. Gillespie; Paula C. Garcia; Nicholas S. Beck (United States Patent and Trademark Office, 2017-08-08)
    Inhalable compositions are described. The inhalable compositions comprise one or more respirable aggregates, the respirable aggregates comprising one or more poorly water soluble active agents, wherein at least one of the ...
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    Enhanced delivery of immunosuppressive drug compositions for pulmonary delivery 

    Robert O. Williams, III; Keith P. Johnston; True L. Rogers; Alan B. Watts; Prapasri Sinswat; Jason T. McConville; Robert Talbert; Jay I. Peters (United States Patent and Trademark Office, 2015-06-02)
    The present invention includes compositions and methods for making and using a rapid dissolving, high potency, substantially amorphous nanostructured aggregate for pulmonary delivery of tacrolimus and a stabilizer matrix ...

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    Author
    Robert O. Williams, III (7)
    Keith P. Johnston (4)Dave A. Miller (3)James W. McGinity (3)Jason T. McConville (3)Jason T. McConville (2)Jay I. Peters (2)Robert Talbert (2)True L. Rogers (2)Alan B. Watts (1)... View MoreSubject
    No longer published (7)
    A61K31/496 (5)A61K38/13 (3)A61K9/146 (3)A61K9/19 (3)A61K31/55 (2)A61K31/58 (2)A61K9/0073 (2)A61K9/008 (2)A61K9/1635 (2)... View MoreDate Issued2017 (3)2015 (2)2016 (2)Department
    Board of Regents, University of Texas System (7)
    Has File(s)Yes (7)

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