Now showing items 11-13 of 13
Control of whole body energy homeostasis by microRNA regulation
(United States Patent and Trademark Office, 2016-08-30)
The disclosure provides a method of regulating fatty acid or glucose metabolism in a cell by contacting the cell with a modulator of miR-208a and/or miR-208b activity or expression. The disclosure also provides a method ...
Micro-RNAS that control myosin expression and myofiber identity
(United States Patent and Trademark Office, 2015-02-24)
The present invention relates to the identification of two microRNAs, miR-499 and miR-208b, that repress fast skeletal muscle contractile protein genes. Expression of miR-499 and/or miR-208b can be used to repress fast ...
Micro-RNAS of the MIR-15 family modulate cardiomyocyte survival and cardiac repair
(United States Patent and Trademark Office, 2013-08-20)
A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, ...