• A Comparative Analysis of Influenza Vaccination Programs 

      Bansal, Shweta; Pourbohloul, Babak; Meyers, Lauren Ancel (Public Library of Science, 2006-10-03)
      Background -- The threat of avian influenza and the 2004–2005 influenza vaccine supply shortage in the United States have sparked a debate about optimal vaccination strategies to reduce the burden of morbidity and mortality ...
    • Enhanced Protection against Ebola Virus Mediated by an Improved Adenovirus-Based Vaccine 

      Richardson, Jason S.; Yao, Michel K.; Tran, Kaylie N.; Croyle, Maria A.; Strong, James E.; Feldmann, Heinz; Kobinger, Gary P. (Public Library of Science, 2009-04-23)
      Background -- The Ebola virus is transmitted by direct contact with bodily fluids of infected individuals, eliciting death rates as high as 90% among infected humans. Currently, replication defective adenovirus-based Ebola ...
    • Erratic Flu Vaccination Emerges from Short-Sighted Behavior in Contact Networks 

      Cornforth, Daniel M.; Reluga, Timothy C.; Shim, Eunha; Bauch, Chris T.; Galvani, Alison P.; Meyers, Lauren Ancel (Public Library of Science, 2011-01-27)
      The effectiveness of seasonal influenza vaccination programs depends on individual-level compliance. Perceptions about risks associated with infection and vaccination can strongly influence vaccination decisions and thus ...
    • The Impact of Imitation on Vaccination Behavior in Social Contact Networks 

      Ndeffo Mbah, Martial L.; Liu, Jingzhou; Bauch, Chris T.; Tekel, Yonas I.; Medlock, Jan; Meyers, Lauren Ancel; Galvani, Alison P. (Public Library of Science, 2012-04-12)
      Previous game-theoretic studies of vaccination behavior typically have often assumed that populations are homogeneously mixed and that individuals are fully rational. In reality, there is heterogeneity in the number of ...
    • Nasal Delivery of an Adenovirus-Based Vaccine Bypasses Pre-Existing Immunity to the Vaccine Carrier and Improves the Immune Response in Mice 

      Croyle, Maria A.; Patel, Ami; Tran, Kaylie N.; Gray, Michael; Zhang, Yi; Strong, James E.; Feldmann, Heinz; Kobinger, Gary P. (Public Library of Science, 2008-10-29)
      Pre-existing immunity to human adenovirus serotype 5 (Ad5) is common in the general population. Bypassing pre-existing immunity could maximize Ad5 vaccine efficacy. Vaccination by the intramuscular (I.M.), nasal (I.N.) or ...
    • Optimizing Tactics for Use of the U.S. Antiviral Strategic National Stockpile for Pandemic Influenza 

      Dimitrov, Nedialko B.; Goll, Sebastian; Hupert, Nathaniel; Pourbohloul, Babak; Meyers, Lauren Ancel (Public Library of Science, 2011-01-19)
      In 2009, public health agencies across the globe worked to mitigate the impact of the swine-origin influenza A (pH1N1) virus. These efforts included intensified surveillance, social distancing, hygiene measures, and the ...