Membrane-Mediated Alterations of Intracellular Na+ and K+ in Lytic-Virus-Infected and Retrovirus-Transformed Cells

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Date

1982_07

Authors

Garry, Robert F.
Ulug, Emin T.
Bose, Henry R.

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Abstract

Infection of chick-embryo fibroblasts and other ceils by certain animal viruses results in alterations in the intracellular concentrations of Na + and K +. Dramatic alterations in monovalent-cation concentrations of lytic-virus-infected ceils may favor the synthesis of viral proteins over cellular proteins. More subtle alterations in retrovirus-transformed cells may result in the expression of many morphological and biochemical changes associated with the transformed phenotype.

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Garry, Robert F., Emin T. Ulug, and Henry R. Bose. "Membrane-mediated alterations of intracellular Na+ and K+ in lytic-virus-infected and retrovirus-transformed cells." Bioscience reports, Vol. 2, No. 8 (Jul., 1982): 617-623.