Comparison of Lateral Flow Technology and Galactomannan and (1 -> 3)-Beta-D-Glucan Assays for Detection of Invasive Pulmonary Aspergillosis

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Date

2009-12

Authors

Wiederhold, Nathan P.
Thornton, Christopher R.
Najvar, Laura K.
Kirkpatrick, William R.
Bocanegra, Rosie
Patterson, Thomas F.

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Journal ISSN

Volume Title

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Abstract

We compared a lateral flow device to galactomannan and (1 -> 3)-beta-D-glucan assays to detect invasive aspergillosis in an established guinea pig model of pulmonary disease. The lateral flow device became positive earlier ( =day 3) than the (1 -> 3)-beta-D-glucan and galactomannan assays ( day 5), with all samples positive by each assay on day 7.

Department

Pharmaceutical Sciences

Description

Keywords

neutropenic patients, enzyme-immunoassay, antifungal therapy, fungal-infections, diagnosis, leukemia, immunology, infectious diseases, microbiology

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Citation

Wiederhold, Nathan P., Christopher R. Thornton, Laura K. Najvar, William R. Kirkpatrick, Rosie Bocanegra, and Thomas F. Patterson. "Comparison of lateral flow technology and galactomannan and (1? 3)-?-D-glucan assays for detection of invasive pulmonary aspergillosis." Clinical and Vaccine Immunology 16, no. 12 (Dec., 2009): 1844-1846.

URI

http://hdl.handle.net/2152/41138

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