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Enantiomeric excess determination using circular dichroism spectroscopy and studies of reversible covalent reactions
(2017-06-14)
The unifying topic of this thesis is that of supramolecular and reversible covalent chemistry. Both supramolecular and reversible covalent reactions operate under thermodynamic control, leading to a proofreading effect and ...
Electron transfer within tetrathiafulvalene calix[4]pyrrole supramolecular ensembles
(2014-12)
Over the last decade, the ecological need for clean and renewable energy sources has resulted in considerable resources being directed toward the development of systems capable of converting light energy into chemical ...
Design and synthesis of artificial receptors for selective and differential sensing
(2007-12)
This dissertation consists of four chapters. The first chapter provides an in-depth background of synthetic receptors for recognitions of phosphorylated molecules. This chapter covers synthetic receptors developed within ...
Synthetic selective and differential receptors for the recognition of bioanalytes
(2006)
This dissertation consists of five chapters. The first chapter provides an in-depth
background of supramolecular chemistry and differential recognition. The first chapter
also elaborates upon the necessary requirements ...
Progress towards a highly efficient and accurate platform for enantiomeric excess determination
(2016-05)
Enantiomeric excess (ee) determination remains as the bottleneck for high throughput screening of asymmetric catalysts. The work described herein sought to expand on two previously developed ee sensing assays from our lab– ...
Studies of anion binding in pyrrole-containing supramolecular motifs
(2002)
Anions are important in a wide range of biological as well as chemical processes. In addition to their importance in the areas of medicine and catalysis, many environmental pollutants are anionic, such as phosphates, ...
Experimental contributions to the theory and application of molecular recognition
(2008-05)
Molecular recognition is a major branch of modern organic chemistry, and it resides at the forefront of supramolecular chemistry. Supramolecular chemistry refers to the study of the noncovalent intermolecular interaction ...
Sensing approaches for the discrimination of small molecules and multivalent analytes
(2014-12)
Differential arrays, composed of receptors that are capable of generating unique patterns of responses, have been shown to be useful for discrimination of molecular analytes. Herein, differential arrays have been developed ...
Exploring chemistry of tetrathiafulvalene-calix[4]pyrroles : supramolecular ion mediated electron transfer
(2010-12)
Molecular recognition exploiting non-covalent interactions mediates the structure and function of many critical biological and synthetic molecules. There has thus been continuing and intense efforts in the design and ...
Synthesis and characterization studies of novel macrocyclic compounds with CH and NH donor groups
(2011-12)
The dissertation focuses on the recent discovery in supramolecular chemistry of novel macrocyclic compounds with NH and CH donor groups. Chapter 1 provides a brief overview of the anions under study, supramolecular chemistry, ...