This dissertation consists of four chapters that focus on various methods and signaling strategies by which different analytes in solution can be detected within a multi-component sensor array. The first chapter of this ...

The dissertation research described here focuses on the fabrication and modification of the polymeric beaded sensing elements, one of the many critical components of a Microbead Array Chip-Based Multianalyte Detection ...

Synthetic molecules that can bind DNA in a sequence specific manner are an interesting area of molecular recognition research with the potential to develop new therapeutics. A novel class of polyintercalators, composed ...

Over the past two decades, the field of molecular sensing has developed into a mature offshoot of molecular recognition, and sensing protocols based on optical signal modulations have enjoyed particularly great success. ...

This dissertation consists of five chapters. The first chapter provides an in-depth background of supramolecular chemistry and differential recognition. The first chapter also elaborates upon the necessary requirements ...

Molecular recognition is a major branch of modern organic chemistry, and it resides at the forefront of supramolecular chemistry. Supramolecular chemistry refers to the study of the noncovalent intermolecular interaction ...

Molecular recognition exploiting non-covalent interactions mediates the structure and function of many critical biological and synthetic molecules. There has thus been continuing and intense efforts in the design and ...

The use of kinetically labile metal ions to template designed interactions between organic ligands in aqueous solutions is described. This strategy is employed to target small biological molecules using coordinatively ...

The ability of electrospray ionization mass spectrometry (ESI-MS) to quantitatively analyze the distribution of complexes resulting from molecular recognition in solution was modeled, and ESI-MS techniques were developed ...