Now showing items 1-5 of 5
Advanced development of ambient ionization mass spectrometry imaging methods and their utilization towards the understanding of metabolic diseases
Ambient ionization mass spectrometry (MS) technologies offer a unique opportunity to bring the specificity and sensitivity of MS into clinics, potentially allowing rapid analyses of biospecimens without need for sample ...
Molecular characterization of biological samples by ambient ionization mass spectrometry to advance clinical assessment of human disease
Ambient ionization mass spectrometry (MS) approaches have revolutionized the way diagnostic molecular information can be obtained from biological and clinical samples, requiring minimal to no sample pretreatment, being ...
Development and application of methods towards the structural characterization of gas-phase biomolecular assemblies
The utility of ultraviolet photodissociation mass spectrometry (UVPD-MS) in native MS approaches, including ion mobility spectrometry (IMS), for protein complexes is described in this dissertation. A modular drift tube ...
Development of ultraviolet photodissociation mass spectrometry strategies for the characterization of biomolecular structure
Ultraviolet photodissociation (UVPD) is an alternative high-energy ion activation technique implemented to produce information rich tandem mass spectra. Dissociation of biomolecules by UVPD results in structure dependent ...
Structural characterization of bacterial lipids using ultraviolet photodissociation mass spectrometry
Glycerophospholipids (GPLs) are one of the main components of bacterial cell membranes, and exhibit high levels of structural complexity that are directly correlated with biophysical membrane properties such as permeability ...