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Development of top-down methods for evaluating protein structure and protein unfolding utilizing 193 nm ultraviolet photodissociation mass spectrometry
(2014-12)
Ultraviolet photodissocation (UVPD) mass spectrometry was used for high mass accuracy top down characterization of two proteins labeled by the chemical probe, S-ethylacetimidate (SETA), in order to evaluate conformational ...
Development of top-down mass spectrometry methods for structural characterization of protein macromolecules utilizing 193nm ultraviolet photodissociation
(2016-08-16)
The dissertation will discuss the advancement of informative structural biology techniques utilizing a top-down centric workflow with 193nm ultraviolet photodissociation (UVPD) mass spectrometry. Native electrospray ...