Now showing items 1-2 of 2
Development of top-down methods for evaluating protein structure and protein unfolding utilizing 193 nm ultraviolet photodissociation mass spectrometry
Ultraviolet photodissocation (UVPD) mass spectrometry was used for high mass accuracy top down characterization of two proteins labeled by the chemical probe, S-ethylacetimidate (SETA), in order to evaluate conformational ...
Development of top-down mass spectrometry methods for structural characterization of protein macromolecules utilizing 193nm ultraviolet photodissociation
The dissertation will discuss the advancement of informative structural biology techniques utilizing a top-down centric workflow with 193nm ultraviolet photodissociation (UVPD) mass spectrometry. Native electrospray ...