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Hybrid activation for intact protein and peptide characterization
Mass spectrometers may be utilized to generate and detect fragmentation patterns of peptides and proteins to acquire mass spectra that allow for accurate amino acid sequence characterization and localization of post-translational ...
Development of mass spectrometric methods for proteomics analysis utilizing gas-phase chemistry and ultraviolet photodissociation
The utility of ultraviolet photodissociation (UVPD) in comparison to higher-energy collisional dissociation (HCD) to provide sequence coverage was assessed for various protein cation charge states and sizes. UVPD provided ...