Browsing UT Electronic Theses and Dissertations by Subject "Zebrafish"
Now showing items 1-7 of 7
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Bisphenol A, and three related alkylphenols exert rapid estrogenic actions on zebrafish (Danio rerio) oocytes to maintain meiotic arrest
(2014-12)Bisphenol A (BPA) is an alkylphenol compound used in plastic manufacturing, which enters the aquatic environment through wastewater treatment plants and landfill leachates. Exposure of fish to BPA results in developmental ... -
Examination of the role of different classes of progesterone receptors in oocyte maturation in zebrafish, Danio rerio
(2007-12)The overall goal of this thesis was to investigate the involvement of three potential progestin receptors in the oocyte maturation of a single model species, zebrafish. Potential mediators of oocyte maturation in lower ... -
Genetic analysis of tendon development and musculoskeletal integration in the vertebrate head
(2017-08-11)We investigated zebrafish mutants that affect craniofacial development to examine how those mutations affect the musculoskeletal patterning of the jaw. We discovered that loss of function in cyp26b1 caused musculoskeletal ... -
The hedgehog pathway in retinal development and disease
(2011-08)The Hedgehog receptor Patched (Ptch) is a well-studied tumor suppressor. Mutations in Ptch have been linked to mis-regulation of stem cell proliferation and tumorigenesis in numerous contexts. To study the role of Ptch ... -
Inhibitor of differentiation 2A influences growth and differentiation of the developing vertebrate retina upstream of the notch signaling pathway
(2012-08)Inhibitor of differentiation (Id) family helix-loop-helix proteins regulate the proliferation, survival and differentiation of numerous cell types during development, however their function during retinal development has ... -
Integrin alphα5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish
(2010-08)Fibronectin (fn) and integrin α5 (itgα5) are both key players in cell adhesion and intracellar signaling, however the specific in vivo role of these proteins has never been analyzed in the vertebrate lens. The results ... -
Roles for zebrafish trpm7 in growth, skeletogenesis, kidney function and physiological ion homeostasis
(2009-12)Development of the adult form requires coordinated growth and patterning of multiple traits in response to local gene activity as well as global endocrine and physiological effectors. In recent years the zebrafish has been ...
