Evaluation Of Etest Method For Determining Isavuconazole MICs Against Cryptococcus Gattii And Cryptococcus Neoformans

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Date

2008-08

Authors

Thompson, George R.
Fothergill, Annette W.
Wiederhold, Nathan P.
Vallor, Ana C.
Wickes, Brian L.
Patterson, Thomas F.

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Abstract

We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8% agreement was found between these methods, without major discrepancies (> 2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.

Department

Pharmaceutical Sciences

Description

Keywords

in-vitro activity, broth macrodilution, antifungal agents, triazole, bal4815, aspergillus, candida, bal8557, prodrug, microbiology, pharmacology & pharmacy

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Citation

Thompson, G. R., Fothergill, A. W., Wiederhold, N. P., Vallor, A. C., Wickes, B. L., & Patterson, T. F. (2008). Evaluation of Etest Method for Determining Isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans . Antimicrobial Agents and Chemotherapy, 52(8), 2959–2961. doi:10.1128/AAC.00646-08

URI

http://hdl.handle.net/2152/31229

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