Energy balance, metabolism and cancer prevention: mechanistic insights from transdisciplinary studies
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The prevalence of obesity, an established risk factor for many cancers, has risen steadily for the past several decades in the US and many other countries. Unfortunately, the mechanisms underlying the obesity and cancer connection are not well understood, and new targets and strategies for offsetting the impact of obesity on cancer risk and/or progression are urgently needed.
Stephen D Hursting is with the Department of Nutritional Sciences, The University of Texas at Austin and Department of Molecular Carcinogenesis, the University of Texas MD Anderson Cancer Center, USA