TexasScholarWorks
    • Login
    • Submit
    View Item 
    •   Repository Home
    • UT Electronic Theses and Dissertations
    • UT Electronic Theses and Dissertations
    • View Item
    • Repository Home
    • UT Electronic Theses and Dissertations
    • UT Electronic Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Studies towards the total synthesis of condylacarpine and studies towards the enantioselective synthesis of (+)-methyl lysergate

    Thumbnail
    View/Open
    deckj18124.pdf (2.475Mb)
    Date
    2007-05
    Author
    Deck, Jason Anthony, 1972-
    Share
     Facebook
     Twitter
     LinkedIn
    Metadata
    Show full item record
    Abstract
    An iminium ion cascade sequence was designed and its implementation attempted to form the pentacyclic core structure of the natural product condylocarpine. Trapping of the transient Pictet-Spengler-type spiroindolenium ion with a latent nucleophile would form two of the five rings of condylocarpine in a regioselective manner. Progress towards the first fully stereocontrolled synthesis of a lysergic acid derivative has been described. The route utilizes intermediates with the appropriate oxidation state for the target, and the two stereocenters are installed via asymmetric catalysis. The d ring and second stereocenter were simultaneously formed via an unprecedented microwave heated asymmetric ring closing metathesis (ARCM).
    Department
    Chemistry
    Description
    text
    Subject
    Condylocarpine
    URI
    http://hdl.handle.net/2152/13191
    Collections
    • UT Electronic Theses and Dissertations

    University of Texas at Austin Libraries
    • facebook
    • twitter
    • instagram
    • youtube
    • CONTACT US
    • MAPS & DIRECTIONS
    • JOB OPPORTUNITIES
    • UT Austin Home
    • Emergency Information
    • Site Policies
    • Web Accessibility Policy
    • Web Privacy Policy
    • Adobe Reader
    Subscribe to our NewsletterGive to the Libraries

    © The University of Texas at Austin

     

     

    Browse

    Entire RepositoryCommunities & CollectionsDate IssuedAuthorsTitlesSubjectsDepartmentsThis CollectionDate IssuedAuthorsTitlesSubjectsDepartments

    My Account

    Login

    Statistics

    View Usage Statistics

    Information

    About Contact Policies Getting Started Glossary Help FAQs

    University of Texas at Austin Libraries
    • facebook
    • twitter
    • instagram
    • youtube
    • CONTACT US
    • MAPS & DIRECTIONS
    • JOB OPPORTUNITIES
    • UT Austin Home
    • Emergency Information
    • Site Policies
    • Web Accessibility Policy
    • Web Privacy Policy
    • Adobe Reader
    Subscribe to our NewsletterGive to the Libraries

    © The University of Texas at Austin