Browsing by Subject "cytotoxic"
Now showing items 1-1 of 1
Part 1: Synthesis of a bicyclic pyran for use as a model study in the synthesis of cytotoxic xanthone IB-00208. Part 2: Progress towards the synthesis of a cyclopropyl-constrained isoleucine residue for studying the effects of preorganization in protein-ligand binding. (2012-05-07)Part 1: Nature is the source of many biologically active molecules that serve as the bases for numerous drugs. One such molecule is IB-00208, a polycyclic xanthone produced by marine bacteria Actinomadura. Despite the ...