• Mechanisms underlying GLI mediated transcriptional regulation 

      Li, Qiang, Ph. D. (2014-12)
      The Hedgehog signaling pathway is an evolutionarily conserved pathway that plays critical roles in both embryogenesis and adult tissue homeostasis. It has been extensively studied in fruit fly, zebra fish and mouse models. ...
    • The role of endoderm in vascular patterning 

      Vokes, Steven Alexander (2002)
      Angioblasts, the precursor cells that give rise to the endothelial layer of blood vessels, arise from a purely mesodermal population. Individual angioblasts coalesce to form the primary vascular plexus through a process ...
    • Transcriptional regulation of sonic hedgehog target genes in the mammalian limb 

      Lewandowski, Jordan Paul (2014-12)
      The Hedgehog (HH) family of secreted proteins are critical regulators of embryonic development. Dysregulation of the HH pathway results in a large class of developmental defects as well as several types of cancer. HH ...