• Fuz Regulates Craniofacial Development through Tissue Specific Responses to Signaling Factors 

    Zhang, Zichao; Wlodarczyk, Bogdan J.; Niederreither, Karen; Venugopalan, Shankar; Florez, Sergio; Finnell, Richard H.; Amendt, Brad A. (Public Library of Science, 2011-09-14)
    The planar cell polarity effector gene Fuz regulates ciliogenesis and Fuz loss of function studies reveal an array of embryonic phenotypes. However, cilia defects can affect many signaling pathways and, in humans, cilia ...
  • Identification of Novel CELSR1 Mutations in Spina Bifida 

    Lei, Yunping; Zhu, Huiping; Yang, Wei; Ross, M. Elizabeth; Shaw, Gary M.; Finnell, Richard H. (PLOS One, 2014-03-14)
    Spina bifida is one of the most common neural tube defects (NTDs) with a complex etiology. Variants in planar cell polarity (PCP) genes have been associated with NTDs including spina bifida in both animal models and human ...
  • Metabolomics of the Tumor Microenvironment in Pediatric Acute Lymphoblastic Leukemia 

    Tiziani, Stefano; Kang, Yunyi; Harjanto, Ricky; Axelrod, Joshua; Piermarocchi; Roberts, William; Paternostro, Giovanni (PLOS One, 2013-12-13)
    The tumor microenvironment is emerging as an important therapeutic target. Most studies, however, are focused on the protein components, and relatively little is known of how the microenvironmental metabolome might influence ...
  • Mutations in Planar Cell Polarity Gene SCRIB Are Associated with Spina Bifida 

    Lei, Yunping; Zhu, Huiping; Duhon, Cody; Yang, Wei; Ross, M. Elizabeth; Shaw, Gary M.; Finnell, Richard H. (PLOS One, 2013-07-26)
    Neural tube defects (NTDs) (OMIM #182940) including anencephaly, spina bifida and craniorachischisis, are severe congenital malformations that affect 0.5–1 in 1,000 live births in the United States, with varying prevalence ...