• Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation 

    Shivaswamy, Sushma; Bhinge, Akshay; Zhao, Yongjun; Jones, Steven; Hirst, Martin; Iyer, Vishwanath R (Public Library of Science, 2008-03-18)
    The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not ...
  • The effect of a three dimensional growth environment on cell death and stress protein expression 

    Song, Alfred Seunghoon (2012-05)
    Understanding the cellular response thermal stress is important for improving thermoablative treatments of cancer. Cells generally respond to thermal stress by expressing heat shock proteins, or undergoing cell death by ...
  • Heat shock-induced apoptosis 

    Mahajan, Indra Maria (2013-12)
    Apoptosis is a conserved program of cell death that promotes organism homeostasis in all stages of life. Two main pathways activate caspases, which are cysteinyl-aspartate proteases that execute apoptosis. The extrinsic ...
  • A Low Concentration of Ethanol Impairs Learning but Not Motor and Sensory Behavior in Drosophila Larvae 

    Robinson, Brooks G.; Khurana, Sukant; Pohl, Jascha B.; Li, Wen-ke; Ghezzi, Alfredo; Cady, Amanda M.; Najjar, Kristina; Hatch, Michael M.; Shah, Ruchita R.; Bhat, Amar; Hariri, Omar; Haroun, Kareem B.; Young, Melvin C.; Fife, Kathryn; Hooten, Jeff; Tran, Tuan; Goan, Daniel; Desai, Foram; Husain, Farhan; Godinez, Ryan M.; Sun, Jeffrey C.; Corpuz, Jonathan; Moran, Jacxelyn; Zhong, Allen C.; Chen, William Y.; Atkinson, Nigel S. (Public Library of Science, 2012-05-18)
    Drosophila melanogaster has proven to be a useful model system for the genetic analysis of ethanol-associated behaviors. However, past studies have focused on the response of the adult fly to large, and often sedating, ...
  • Mechanisms of benzyl alcohol tolerance in Drosophila melanogaster 

    Alhasan, Yazan Mahmoud (2009-12)
    Proper neuronal function requires the preservation of appropriate neural excitability. An adaptive increase in neural excitability after exposure to agents that depress neuronal signaling blunts the sedative drug effects ...