Browsing by Subject "C40B30/04"

Now showing 1 - 5 of 5

Peptide mediated synthesis of metallic and magnetic materials
(United States Patent and Trademark Office, 2008-05-20) Brian D. Reiss; Angela M. Belcher; Chuanbin Mao; Daniel J. Solis; Board of Regents, The University of Texas System
The present invention includes methods for producing magnetic nanocrystals by using a biological molecule that has been modified to possess an amino acid oligomer that is capable of specific binding to a magnetic material.
Peptide mediated synthesis of metallic and magnetic materials
(United States Patent and Trademark Office, 2015-03-03) Brian D. Reiss; Angela M. Belcher; Chuanbin Mao; Daniel J. Solis; Board of Regents, The University of Texas System
The present invention includes methods for producing magnetic nanocrystals by using a biological molecule that has been modified to possess an amino acid oligomer that is capable of specific binding to a magnetic material.
Proteomic identification of antibodies
(United States Patent and Trademark Office, 2015-09-29) George M. Georgiou; Edward M. Marcotte; Jason Lavinder; Daniel Boutz; Yariv Wine; Board of Regents, The University of Texas System
Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects, methods for determining amino acid sequences of serum antibody CDR3 and abundancy levels are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and the frequency thereof in biological samples are provided. Furthermore, the invention provides methods for identification and generation of antibodies or antigen-binding fragments that comprise highly-represented CDR domains.
Proteomic identification of antibodies
(United States Patent and Trademark Office, 2019-01-08) George M. Georgiou; Edward M. Marcotte; Jason Lavinder; Daniel Boutz; Yariv Wine; Board of Regents, The University of Texas System
Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects, methods for determining amino acid sequences of serum antibody CDR3 and abundancy levels are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and the frequency thereof in biological samples are provided. Furthermore, the invention provides methods for identification and generation of antibodies or antigen-binding fragments that comprise highly-represented CDR domains.
Rapid isolation of monoclonal antibodies from animals
(United States Patent and Trademark Office, 2015-07-28) George M. Georgiou; Andrew D. Ellington; Edward M. Marcotte; Sai T. Reddy; Xin Ge; Jason Lavinder; Daniel Boutz; The Board of Regents of the University of Texas System
Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects methods for determining amino acid sequences of serum antibody CDR and abundancy level are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and frequency are provided. Furthermore, the invention provides methods for identification and generation of antibody or antigen-binding fragments that comprise highly-represented CDR.