| dc.contributor.advisor |
Magnus, Philip D. |
| dc.creator |
Rivera, Heriberto
|
| dc.date.accessioned |
2012-01-27T21:25:35Z |
| dc.date.available |
2012-01-27T21:25:35Z |
| dc.date.created |
2011-12 |
| dc.date.issued |
2012-01-27 |
| dc.date.submitted |
December 2011 |
| dc.identifier.uri |
http://hdl.handle.net/2152/ETD-UT-2011-12-4421 |
| dc.description.abstract |
Herein we describe the synthesis of (±) platensimycin, a potent antibiotic against gram-positive bacteria. The first chapter reviews (±) platensimycin’s isolation, biological profile and previously reported studies relevant to the area. The second chapter describes our initial efforts to synthesize (±) platensimycin. The third chapter accounts our second generation synthesis and its completion. The fourth chapter entails the experimental details of the important compounds in our synthesis. |
| dc.format.mimetype |
application/pdf |
| dc.language.iso |
eng |
| dc.subject |
Platensimycin
|
| dc.subject |
Synthesis
|
| dc.subject |
Antibiotic
|
| dc.title |
A direct, concise and stereoselective formal synthesis of platensimycin |
| dc.date.updated |
2012-01-27T21:25:48Z |
| dc.identifier.slug |
2152/ETD-UT-2011-12-4421 |
| dc.contributor.committeeMember |
Krische, Michael J. |
| dc.contributor.committeeMember |
Jones, Richard M. |
| dc.contributor.committeeMember |
Siegel, Dionicio R. |
| dc.contributor.committeeMember |
Kerwin, Sean M. |
| dc.description.department |
Chemistry
|
| dc.type.genre |
thesis |
| dc.type.material |
text |
| thesis.degree.department |
Chemistry
|
| thesis.degree.discipline |
Chemistry |
| thesis.degree.grantor |
University of Texas at Austin |
| thesis.degree.level |
Doctoral |
| thesis.degree.name |
Doctor of Philosophy |
