A direct, concise and stereoselective formal synthesis of platensimycin

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A direct, concise and stereoselective formal synthesis of platensimycin

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dc.contributor.advisor Magnus, Philip D.
dc.creator Rivera, Heriberto
dc.date.accessioned 2012-01-27T21:25:35Z
dc.date.available 2012-01-27T21:25:35Z
dc.date.created 2011-12
dc.date.issued 2012-01-27
dc.date.submitted December 2011
dc.identifier.uri http://hdl.handle.net/2152/ETD-UT-2011-12-4421
dc.description.abstract Herein we describe the synthesis of (±) platensimycin, a potent antibiotic against gram-positive bacteria. The first chapter reviews (±) platensimycin’s isolation, biological profile and previously reported studies relevant to the area. The second chapter describes our initial efforts to synthesize (±) platensimycin. The third chapter accounts our second generation synthesis and its completion. The fourth chapter entails the experimental details of the important compounds in our synthesis.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.subject Platensimycin
dc.subject Synthesis
dc.subject Antibiotic
dc.title A direct, concise and stereoselective formal synthesis of platensimycin
dc.date.updated 2012-01-27T21:25:48Z
dc.identifier.slug 2152/ETD-UT-2011-12-4421
dc.contributor.committeeMember Krische, Michael J.
dc.contributor.committeeMember Jones, Richard M.
dc.contributor.committeeMember Siegel, Dionicio R.
dc.contributor.committeeMember Kerwin, Sean M.
dc.description.department Chemistry
dc.type.genre thesis
dc.type.material text
thesis.degree.department Chemistry
thesis.degree.discipline Chemistry
thesis.degree.grantor University of Texas at Austin
thesis.degree.level Doctoral
thesis.degree.name Doctor of Philosophy

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